I Don’t Know What LADDER Is

Not sure what the Dup15q Medical Database is through LADDER?

Your loved one’s medical data is the best chance of finding new and improved therapeutics for dup15q syndrome.

LADDER was developed by the ASF and Dup15q Alliance, in partnership with RTI International, in response to a critical need for a centralized database to collect and manage the information provided by parents, caregivers, clinicians, and researchers about the natural history and clinical needs of patients with Angelman or Dup15q.

LADDER aims to:

  • Provide new information to researchers, clinicians, and families about the characteristics and clinical needs of individuals living with Angelman or dup15q syndrome.
  • Help further our understanding of potential links between types of genetic mutation and symptom severity.
  • Expand our understanding of the experiences of individuals with Angelman or dup15q and their families across the lifespan by collecting information at different times as they age.
  • Facilitate the development and testing of new therapeutics.

For more information on LADDER visit: LADDER Learning Network

How You Can Help:

Family members of individuals with dup15q syndrome are important allies in the road to developing treatments for these conditions and, in many cases, families have already contributed data elsewhere. LADDER Learning Network and LADDER Database maximizes those contributions by combining those data into a centralized platform, which streamlines research efforts focused on answering important questions about dup15q.