Ride for a Reason with Dup15q In the 2024 Million Dollar Bike Ride!

June 8th, 2024 

University of Pennsylvania campus in downtown Philadelphia


Dup15q Alliance is thrilled to be selected as a charity organization for the 2024 Orphan Disease Center Million Dollar Bike Ride! 

The Million Dollar Bike Ride raises critical funds for rare disease research. For each rare disease team that raises a minimum of $20k, the Orphan Disease Center will match it, dollar for dollar, up to $30k, to be used to support a 1-year pilot grant for new dup15q research!  That’s up to $60,000 in research funds for dup15q syndrome!


How can you help?

Volunteer: We need 5 volunteers for the Day of the Event. Interested? Register HERE or  Email

Ride: We need 10 Fundraiser Riders for the Day of the event. You can ride 10, 32 or 70 miles starting in the city, and ranging across the Greater Philadelphia region.

Walk the Million Dollar Mile:  Those who are not cycling are welcome to walk the Million Dollar Mile! You must be registered to participate.

Make a donation: Team Dup15q will need to raise $20,000 to get the matching funds.

Let’s Ride!

Registration with Fundraising Fee: $30 
(ODC requires each rider to raise a minimum of $250 by June 8th)

Registration with OPTIONAL Fundraising Fee: $65
(Fundraising is not required for this registration)

Let’s Walk!

Registration with Fundraising Fee: $15
Please note, this is for walkers, strollers and adaptive mobility equipment only. No bicycles or scooters permitted. All children must be accompanied by an adult.
The walk begins at 8:00AM – shortly after all cyclists are off! The route will be closed to traffic until all walkers return to the start/finish line.

During registration, you will be asked to join Team Dup15q. If you are fundraising, your fundraising efforts will be linked to Team Dup15q.

After registration, you will be able to set up your fundraising page within Pledge It. Pledge It will also send you a separate email on how to access your fundraising page for future edits and use.

Registration with Fundraising includes this year’s Cycling Jersey!

100% of your fundraising dollars go to Team Dup15q Research Grant.

Donations are processed solely by The University of Pennsylvania. Tax ID Number is 23-1352685. Contact for donation receipts or other related questions.

Make an impact on Dup15q Research

In 2023, Dup15q families raised over $47,000 to fund a research grant to: Jason Yi at Washington University School of Medicine

Deep phenotyping of mouse models of UBE3A gain-of-function