Dup15q Alliance Research Grant Program- Letter of Intent Submission

Due to the uncertainty of the COVID-19 environment, the 2020 RFA will be delayed until further notice.

Letter of Intent for Dup15q Alliance Research Grant Introduction

Researchers funded by the Dup15q Alliance have a strong history of obtaining additional funding: between 2014 and 2018, principal investigators who received a total of $400,000 from the Dup15q Alliance subsequently garnered an additional $2.5 million from the NIH for dup15q syndrome-related research.

Dup15q Alliance invites submission of Letters of Intent for the Dup15q Alliance Research Grant Program. All proposals must be scientifically linked to the Dup15q syndrome.


This funding opportunity is open to independent investigators at established academic or research institutions worldwide. The Dup15q Alliance Research Grant Program encourages applications from investigators within the first few years of establishing their laboratories and from established investigators venturing into new projects focused on Dup15q syndrome.  Researchers residing in the United States do not need to be U.S. citizens to apply for funding.

  • Duration: up to two years

  • Budget limits: Maximum total costs of $50,000 per year ($100,000 total) direct costs only.  The award may support laboratory supplies, personnel costs, services, or equipment necessary to conduct the proposed research.

  • Research projects should address one of the following four high-priority areas:

    • Understanding phenotypic heterogeneity in Dup15q, i.e., contributions of genetic, biologic, or environmental factors.

    • Defining the neurobiological and neurophysiological underpinnings of the Dup15q using cellular, animal or human systems.

    • Dup15q disease models, whether cell-based, tissue-based, or animal models.

    • Developing and validating clinical biomarkers or patient-reported outcome measures, particularly those that assess disease burden or stratify an individual’s risk of progression or developing specific manifestations of Dup15q syndrome.

Application Process:

Applications will only be accepted through the online submission system.  

Applicants must submit

  1. Project Title
  2. A brief letter of intent including project summary and outlining the specific aims, rationale and approach.  The investigator should state relevance to Dup15q syndrome (1 page maximum.  No figures.)
  3. PI Biosketch (NIH-format)
Font, Spacing and Page Numbering

All pages should be single spaced, 11 pt. Arial font with 0.5 inch margins.

Number pages at top right or bottom center prior to converting to pdf.