Clinical study for children with Dup15q Syndrome
The Quindecim clinical research study, sponsored by a pharmaceutical company called Roche, is testing the medication Basmisanil in children with Dup15q Syndrome.
Basmisanil is a drug that modulates the activity of a GABAA receptor subtype that is thought to be overactive in dup15q syndrome. In this trial, researchers aim to find out what effects, good or bad, Basmisanil may have compared to a placebo, on motor, language, and social skills of children with Dup15q syndrome and on their ability to do day-to-day activities.
Watch the conference replay below with Dr. Shafali Jeste to learn more about GABAA in dup15q and the dup15q eeg biomarker.Â
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Enrollment
Quindecim study is currently running and plans to include about 90 children with Dup15q syndrome, between the ages of 2 and 11 years old (inclusive) some locations are enrolling ages 2-14.Â
Important:Â If your child does not meet current eligibility requirements, please check back as it is projected two additional groups may open.
For General Questions call 1-888-662-6728.
Current US Locations Enrolling:Â *more locations expected to open in 2023
RUSH University Medical Center in Chicago
1620 W. Harrison St., Chicago, IL 60612
Currently enrolling ages 2 – 14. Interested in Enrolling at Rush?
Contact Margaret_R_Porwit@rush.edu
University of North Carolina at Chapel Hill
Currently enrolling ages 2 – 11. Interested in Enrolling at UNC?
Contact victoria_banks@neurology.unc.edu
Phone: (919) 962-5137
Children’s Hospital Los AngelesÂ
4650 W Sunset Blvd, Los Angeles, CA 90027
Currently enrolling ages 2 – 11. Interested in Enrolling at CHLA?
Contact nagonzalez@chla.usc.edu
Rady Children’s Hospital San Diego
3020 Children’s Way, San Diego, CA 92123
Currently enrolling ages 2 – 14. Interested in Enrolling at Rady?
Contact: mnsuarez@rchsd.org
Phone: 858.576.1700 Ext: 226134
Learn More
To learn more about the study, please talk to your doctor and check the following resources: